Center for Sports Medicine & Orthopaedics
OrthoBiologics Program

OrthoBiologics refers to the processes by which specialized technology is used to create living, functional tissues to replace or repair tissue that has been lost due to damage, disease, or hereditary defects. For those struggling with limited mobility due to arthritis, injury, tendinopathy (disease of the tendons), or other forms of musculoskeletal inflammation, patients may be able to experience relief and avoid surgery by harnessing the healing potential of their own cells.

Adipose-Derived Cell Therapies

This method utilizes fat cells, which have high concentrations of messenger cells and other growth factors within them, to decrease inflammation and aid in healing. In a minimally invasive procedure, a doctor will retrieve a patient’s own fat cells and deposit them into a device that uses a saline agent to rid the cells of blood and oil. At that point, the fat tissue has been resized and holds the ideal material and performance properties to stimulate healing. The doctor will then inject the fat graft into the joint experiencing the arthritic pain to decrease inflammation and encourage healing.


Platelet Rich Plasma

Commonly referred to as PRP, platelet rich plasma utilizes a patient’s own blood to produce growth factors. Growth factors are naturally occurring proteins that bind to the cells in your body and stimulate growth, healing, and repopulation. With this minimally invasive procedure, a doctor will draw the patient’s blood and spin it in a centrifuge to separate the blood into layers. The layer, which is rich with growth factors and platelets, is extracted and reintroduced into the damaged joint to encourage healing and reduce inflammation.

Bone Marrow Aspirate

Bone marrow – the soft, spongy tissue found in the center of large bones – is composed of both fluid and solid matter. It is rich in growth factors and messenger cells. Unlike other cells in the body, these cells are able to replicate themselves into various types of tissue for healing. To utilize bone marrow to stimulate healing and regrowth in an arthritic joint, a doctor will extract bone marrow fluid (called aspirate) from a healthy bone in the body, generally the pelvis, and place it in a centrifuge to generate a concentration of powerful cells. These cells are then reintroduced into the arthritic joint to repair damaged tissue and decrease inflammation.

These procedures are some of the newest treatments available today. They offer patients a minimally invasive option to help relieve the pain of arthritis or injury and improve function. Our highly skilled medical doctors use state-of-the-art diagnostic tools, including musculoskeletal untrasound, high-definition on-site MRI, and X-ray, to obtain pinpoint accuracy during the procedures.


What is the iovera° treatment?
The ioverao treatment uses the body’s natural response to cold to treat peripheral nerves and immediately reduce pain – without the use of drugs. Treated nerves are temporarily stopped from sending pain signals for a period of time, followed by a restoration of function.

It is important to note that the ioverao therapy does not treat the underlying cause of the pain.  Timely remediation is necessary to address and treat the cause of pain.

How does iovera° treatment work?
The ioverao treatment works by applying targeted cold to a peripheral nerve.  A precise cold zone is formed under the skin – cold enough to immediately prevent the nerve from sending pain signals without causing damage to surrounding structures.  The effect on the nerve is temporary, providing pain relief until the nerve regenerates and function is restored.

The ioverao treatment does not include injection of any substance- drugs, opioids or narcotics.  The effect of this treatment is immediate and can last up to 90 (ninety) days.

Is the iovera° treatment for me?
If your pain is chronic, due to osteoarthritis, it can be alleviated by cryoanalgesia with the ioverao treatment.  The ioverao system has also been shown to help in reducing opioid consumption in patients after surgery.  Post-surgical pain is considered to be acute pain.

The ioverao treatment is a focused therapy.  Therefore, there are no systemic side effects that are typically experienced with NSAIDs, narcotics or other medications.  Nothing is injected into the treatment area by the ioverao system.  Therefore, very few, if any, localized side effects due to the ioverao treatment have been observed and side effects are mild

Consult with your physician to determine if cryoanalgesia with the ioverao system will benefit you.

Fewer Opioid Prescriptions

Patients who received the ioverao treatment requested 45% fewer opioid prescriptions at 12 weeks after knee replacement surgery.*

Reduction in Knee Pain

12 weeks after surgery, the majority of patients who received the ioverao treatment experienced less pain.*

Faster Recovery

Post-surgical recovery was much faster in patients who received the ioverao treatment before knee replacement surgery.*

*Dasa, V. et al. “Percutaneous freezing of sensory nerves prior to total knee arthroplasty.” The Knee (2016) p523-528.

GEL monodoses: P3 AI and P3 RG

A pain management line of products for optimum joint and soft tissue wellness.

P3 line of monodoses contains SIGMOLECS®Technology in that it designs scaled molecules that can easily penetrate the skin and enter deep tissue. The shorter the AA sequence, the better the penetration, so molecules are fashioned according to sequences that are ‘skin friendly’ and can facilitate navigation through cell membranes. Using native peptides from pork collagen, for example, provides a chemical template to structure therapeutic specificity in a repair combination such as P3 RG; or an anti-inflammatory and anti-nociceptive pathway as in the P3 AI. The basic gel amalgam provides structural molecules conducive to crossing skin and cell barriers, and in this sense, is a completely functional product that is both a carrier and a therapeutic gel.

Make an appointment with one of our industry-leading physicians today to see if OrthoBiologics is an option for you by calling (423) 697-8780.

The physicians at Center for Sports Medicine and Orthopaedics are highly regarded as leaders in their profession, not only in Chattanooga, but in the Southeast region. They continue to be at the forefront of offering patients the latest medical procedures and treatments toward ensuring the best possible outcomes. We are excited to offer our patients an innovative approach to treating pain and healing.

At Center for Sports Medicine & Orthopaedics, our highly trained and compassionate staff takes pride in providing personalized care to all of our patients. That starts with a full orthopaedic evaluation with one of our doctors to assess your needs and evaluate your treatment options. We have specialists who focus on specific areas of the body including the spine, shoulder, hand, elbow, hip, knee, foot and ankle.

Make an appointment with one of our industry-leading physicians today to see if OrthoBiologics is an option for you by calling (423) 697-8780.
2415 McCallie Avenue
Chattanooga, Tennessee 37404

OrthoBiologics Physicians

Email Us or call Tabitha Taylor at (423) 697-8780 to schedule an appointment with one of our industry-leading physicians to see if OrthoBiologics is an option for you.